Attomarker has developed a COVID19 Antibody Immunity test which is CE marked and is fully quantitative referenced to the NIST standard human antibody. The test measures the antibody immunity profile for antibodies binding to spike, omicron-spike, nucleocapsid and receptor binding domain proteins. Antibody Immunity profile (Figure 5) provides the following information:
- Nucleocapsid (N) indicating past viremia;
- Spike Protein (S) indicating past infection or vaccination;
- Spike Protein from the Omicron Variant (SO) indicating vaccine binding to the Omicron variant or infection from Omicron;
- Receptor Binding Domain (RBD)
The test also measures the familiar C Reactive Protein. The Test is performed currently from venous blood for accuracy with the results available in 7 minutes, presented as the Biomark (Figure 5) available on the iPhone app.
The concentration of S antibodies is used to assess the number of ‘Immunity Days’ to the ‘Edge of Immunity’ calculated from an antibody half-life of 60 days and a mucosal protection threshold of 3.4 mg/L, rounded to the nearest month.
The Edge of Immunity depends on your antibody half-life and ranges from 60 – 200 days. The test can measure your precise half-life but we would need to take two samples 100 days apart. Your doctor can be advised on whether this is important to you.
The test is usually sold as part of a consultation in private healthcare to patients who believe they are immuno-compromised, preparing to travel, have vulnerable relatives or considering whether to have a booster jab or not.